A human recombinant protein was used as the immunogen for this MMP2 antibody.
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. [UniProt]
The stated application concentrations are suggested starting points. Titration of the MMP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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