Amino acids 214-248 from the human protein were used as the immunogen for this NSFL1C antibody.
Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER) (By similarity). Inhibits the activity of CTSL (in vitro).
The stated application concentrations are suggested starting points. Titration of the NSFL1C antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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