A portion of amino acids 298-330 from the human protein was used as the immunogen for the LIAS antibody.
Lipoic acid synthetase catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
