A portion of amino acids 215-246 from the human protein was used as the immunogen for the G6PC3 antibody.
Glucose 6 phosphatase, catalytic, 3 hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function.