A portion of amino acids 195-224 from the human protein was used as the immunogen for this SMAD7 antibody.
SMAD7 is a member of the MAD-related family of molecules. MAD-related proteins are a recently identified family of intracellular proteins that are thought to be essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta super family.