A portion of amino acids 359-387 from the human protein was used as the immunogen for this ABCG1 antibody.
ATP-binding cassette sub-family G member 1 is a transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.