A portion of amino acids 736-770 from the human protein was used as the immunogen for this Amyloid beta antibody.
APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Abeta is the main component of amyloid plaques (extracellular deposits found in the brains of patients with Alzheimers disease).[19] Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis (a muscle disease), while Abeta can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. [Wiki]
