This phospho-KLF4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS245 of human KLF4.
Krueppel-like factor family members are involved in growth regulation and a wide range of developmental processes. KLF4 is highly expressed in epithelial tissues including skin and stomach/intestine. Studies have shown that it can function as both an oncogene, upregulating hSSC, and a tumor suppressor, down-regulating colorectal cancer.
