PF-3644022 (Standard), CAS [[1276121-88-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-107427R
Hersteller Artikelnummer:
HY-107427R
Alternativnummer:
MCE-HY-107427R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
PF-3644022 (Standard) is the analytical standard of PF-3644022 (HY-107427). This product is intended for research and analytical applications. PF-3644022 is a potent, selective, orally active and ATP-competitive MAPKAPK2 (MK2) inhibitor with an IC50 of 5.2 nM and a Ki of 3 nM. PF-3644022 also inhibits MK3 and p38 regulated/activated Kinase (PRAK) with IC50s of 53 nM and 5.0 nM, respectively. PF-3644022 potently inhibits TNFalpha production and has anti-inflammatory effect[1].
Molekulargewicht:
374.46
CAS Nummer:
[1276121-88-0]
Formel:
C21H18N4OS
Target-Kategorie:
MAPKAPK2 (MK2),p38 MAPK,Reference Standards
Anwendungsbeschreibung:
MCE Product type: Reference Standards
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