AX-024 hydrochloride (Standard), CAS [[1704801-24-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-107390AR
Hersteller Artikelnummer:
HY-107390AR
Alternativnummer:
MCE-HY-107390AR-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
AX-024 hydrochloride (Standard) is the analytical standard of AX-024 (hydrochloride) (HY-107390A). This product is intended for research and analytical applications. AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM. AX-024 hydrochloride modulates cell signaling by targeting SH3 domains. AX-024 hydrochloride has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-alpha, IFN-gamma, IL-10 and IL-17A.
