Phospho-IRE1 (Ser724) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE02857
Produktübersicht
Artikelname:
Phospho-IRE1 (Ser724) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE02857
Hersteller Artikelnummer:
AMRe02857
Alternativnummer:
EKL-AMRE02857-50UL, EKL-AMRE02857-100UL
Hersteller:
EnkiLife
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IP, WB
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Alternative Synonym:
ERN1, IRE1, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, hIRE1p, Ire1-alpha, IRE1a
Produktbeschreibung
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Produkteigenschaften
Klonalität:
Monoclonal
Molekulargewicht:
Calculated MW: 110 kDa, Observed MW: 110 kDa
NCBI:
2081
UniProt:
O75460
Puffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Reinheit:
Affinity Purification
Formulierung:
Liquid
Target-Kategorie:
ERN1
Anwendungsbeschreibung
Application Verdünnung:
WB 1:500-1:1000,IP 1:20-1:50
