Myosin Heavy Chain, Smooth Muscle(SMMHC) Mouse Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMM22136
Hersteller Artikelnummer:
AMM22136
Alternativnummer:
EKL-AMM22136-50UL, EKL-AMM22136-100UL
Hersteller:
EnkiLife
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
ELISA, IF, IHC
Spezies Reaktivität:
Human, Mouse, Rat
Konjugation:
Unconjugated
Alternative Synonym:
Myosin-11,Myosin heavy chain 11,Myosin heavy chain, smooth muscle isoform,SMMHC,
The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3 end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alter
