Synthesized peptide derived from human OASL. at AA range: 1-50
Alternative Synonym:
2-5-oligoadenylate synthase-like protein (2-5-OAS-related protein) (2-5-OAS-RP) (59 kDa 2-5-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)
caution:This may not be the true ortholog of mouse OASL.,function:Does not have 2-5-OAS activity, but binds double-stranded RNA and DNA.,induction:By interferons.,similarity:Belongs to the 2-5A synthetase family.,similarity:Contains 2 ubiquitin-like domains.,subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR). TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1.,tissue specificity:Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.,
Western Blot analysis of HELA cells using primary antibody diluted at 1:2000(4C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25C, 1 hour)
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