Synthesized peptide derived from BCL2L12 . at AA range: 60-140
Alternative Synonym:
BCL2L12, BPR, Bcl-2-like protein 12, Bcl2-L-12, Bcl-2-related proline-rich protein
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
