The antiserum was produced against synthesized peptide derived from human Ezrin around the phosphorylation site of Tyr353. AA range:321-370
Alternative Synonym:
EZR, VIL2, Ezrin, Cytovillin, Villin-2, p81
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008],
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Western blot analysis of lysates from A431 cells treated with EGF 200ng/ml 30, using Ezrin (Phospho-Tyr353) Antibody. The lane on the right is blocked with the phospho peptide.
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