The antiserum was produced against synthesized peptide derived from human Tuberin/TSC2. AA range:1428-1477
Alternative Synonym:
TSC2, TSC4, Tuberin, Tuberous sclerosis 2 protein
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Tuberin/TSC2 Antibody. The picture on the right is blocked with the synthesized peptide.
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