The antiserum was produced against synthesized peptide derived from human KLF10/11. AA range:391-440
Alternative Synonym:
KLF10, TIEG, TIEG1, Krueppel-like factor 10, EGR-alpha, Transforming growth factor-beta-inducible early growth response protein 1, TGFB-inducible early growth response protein 1, TIEG-1, KLF11, FKLF, TIEG2, Krueppel-like factor 11, Transfor
This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KLF10/11 Antibody. The picture on the right is blocked with the synthesized peptide.
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