Human Carbonic Anhydrase IX / CA9 (138-414) Protein, Unconjugated Preis auf Anfrage
Artikelnummer:
BYT-ORB334937
Hersteller Artikelnummer:
orb334937
Alternativnummer:
BYT-ORB334937-1,BYT-ORB334937-50
Hersteller:
Biorbyt
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Alternative Synonym:
CAIX,CA9,CA-IX,G250,MN,P54,58N,pMW1
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. There are at least five distinct CA families (alpha, beta, gamma, delta and epsilon). Carbonic anhydrase 9 (CA9 / CAIX) is also known as Membrane antigen MN (MN), Renal cell carcinoma-associated antigen G250, which belongs to the alpha-carbonic anhydrase family. CA9 / CAIX with an optimal activity at pH 6.49. Reversible hydration of carbon dioxide. CA IX participates in pH regulation. CA9 may be involved in the control of cell proliferation and transformation. CA-IX appears to be a novel specific biomarker for a cervical neoplasia.
Application Notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30.9 kDa. The protein migrates as 34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation
SDS-PAGE analysis of Human Carbonic Anhydrase IX protein
SDS-PAGE analysis of Human Carbonic Anhydrase IX protein
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