LY393615 is a dual neuronal calcium and sodium channel blocker with IC50 values of 1.9 µM (alpha1A) and 5.2 µM (alpha1B). Its brain-penetrant properties support its use in neuroprotection research, as evidenced by efficacy in cerebral ischemia models for studying stroke and related neurological disorders.
Target-Kategorie:
Sodium Channel,Calcium Channel
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