PI3Kdelta-IN-12 (compound 13) is a selective PI3Kdelta inhibitor with a pIC50 of 5.8, demonstrating high affinity for PI3Kdelta (pKi=8.0) over other PI3K isoforms. It is a research tool used in preclinical studies, including in vitro and in vivo models, to investigate chronic respiratory diseases such as asthma and COPD.
Molekulargewicht:
444.27
Formel:
C20H15Cl2N5O3
Target-Kategorie:
PI3K
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