PTP1B/AKR1B1-IN-2 (Compound 7f) is a dual-target inhibitor of PTP1B and AKR1B1 with IC50 values of 3.2 and 2.1 µM, respectively. It functions as an insulin mimetic, promoting glucose uptake in C2C12 myoblasts, which supports its application in Type 2 diabetes mellitus (T2DM) research for investigating insulin signaling and metabolic pathways.
Molekulargewicht:
441.56
Formel:
C23H23NO4S2
Target-Kategorie:
Phosphatase,Reductase
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