COX-2-IN-33 (5f) is a potent and selective cyclooxygenase-2 inhibitor with an IC50 of 45.5 nM. This compound demonstrates anti-inflammatory activity by reducing pro-inflammatory cytokine levels in vivo and shows a favorable gastric safety profile, making it a useful research tool for inflammation studies.
Molekulargewicht:
479.8
Formel:
C20H13ClF3N5O4
Target-Kategorie:
COX
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