MTase-IN-1 (compound 26) is a highly potent and selective nsp14 N7-methyltransferase inhibitor for coronaviruses, with an IC50 of 0.72 nM. It functions by impairing viral RNA translation and blocking a key viral immune evasion mechanism, making it a valuable tool for antiviral research in both biochemical and cellular assays.
Molekulargewicht:
627.67
Formel:
C31H29N7O6S
Target-Kategorie:
SARS-CoV
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