ABCB1-IN-1 is a potent, small molecule ABCB1 inhibitor featuring a 1-benzylimidazole core. It demonstrates pro-apoptotic activity in vitro with IC50 values of 1.26 µM in Colo205 cells and 2.21 µM in Colo320 cells. This compound is a useful research tool for studying multidrug resistance and oncology pathways in cellular models.
Molekulargewicht:
733.54
Formel:
C36H33F3FeN2O4PS
Target-Kategorie:
P-gp,Others
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