PotassiumChannel, Potassium Channel, GR7, GR-7, GR 7, Gut restricted 7, Gut restricted7, Gut restricted-7, gut-restricted, gut, Nontoxic, inhibit, Inhibitor, orally, acid, Bacterial, bile, Bile salt hydrolase (BSH), BSH
GR-7 is a covalent, orally active pan-bile salt hydrolase (BSH) inhibitor. It effectively reduces gut bacterial BSH activity, leading to decreased fecal deconjugated bile acid levels in mice, making it a valuable tool for researching microbiome-host metabolism interactions in vivo.
