inhibit, INH, INH 154, INH154, INH-154, INH in Hela cells, INH in MB468 cells, Inhibitor
INH154 is a potent small molecule inhibitor targeting the Nek2-Hec1 interaction, exhibiting IC50 values of 120 nM in MB468 cells and 200 nM in Hela cells. It serves as a valuable research tool for studying mitotic regulation and has been utilized in both in vitro and in vivo cancer model studies to investigate potential anti-tumor mechanisms.