IRAK4-IN-4, CAS [[1850276-58-2]]

Artikelnummer: BYT-ORB1309540
Artikelname: IRAK4-IN-4, CAS [[1850276-58-2]]
Artikelnummer: BYT-ORB1309540
Hersteller Artikelnummer: orb1309540
Alternativnummer: BYT-ORB1309540-1, BYT-ORB1309540-1, BYT-ORB1309540-10, BYT-ORB1309540-100, BYT-ORB1309540-25, BYT-ORB1309540-5, BYT-ORB1309540-50
Hersteller: Biorbyt
Kategorie: Biochemikalien
Alternative Synonym: Inhibitor, Interleukin-1 receptor associated kinase, IL-1R associated kinase, IRAK, IRAK4IN4, IRAK-4-IN-4, IRAK4-IN-4, IRAK4, IRAK4 IN 4, inhibit, cGAS, Cyclic GMP-AMP synthase, Cyclic GMP-AMP Synthase
IRAK4-IN-4 is a potent dual-target inhibitor, demonstrating high activity against both cyclic GMP-AMP synthase (cGAS, IC50 = 2.1 nM) and interleukin-1 receptor-associated kinase 4 (IRAK4, IC50 = 2.8 nM). This compound is a valuable research tool for investigating innate immune signaling pathways, including the cGAS-STING and TLR/IL-1R axes, in both cellular and biochemical studies.
Molekulargewicht: 340.37
Reinheit: 99.52% (May vary between batches)
CAS Nummer: [1850276-58-2]
Formel: C22H16N2O2
Target-Kategorie: cGAS,IRAK
Anwendungsbeschreibung: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.88 mM),DMSO:24 mg/mL (70.51 mM)