RIPK1-IN-7, CAS [[2300982-44-7]]
Artikelnummer:
BYT-ORB1309159
Produktübersicht
Artikelname:
RIPK1-IN-7, CAS [[2300982-44-7]]
Artikelnummer:
BYT-ORB1309159
Hersteller Artikelnummer:
orb1309159
Alternativnummer:
BYT-ORB1309159-1,BYT-ORB1309159-5,BYT-ORB1309159-10,BYT-ORB1309159-25,BYT-ORB1309159-50,BYT-ORB1309159-100
Hersteller:
Biorbyt
Kategorie:
Biochemikalien
Alternative Synonym:
Axl, Flt4, HRI, Mer, Inhibitor, inhibit, Receptor-interacting protein kinases, RIPK, RIP kinase, RIPK1, RIPkinase, RIPK1 IN 7, RIPK1IN7, RIPK-1-IN-7, RIPK1-IN-7, TrkA, TrkC, TrkB
Produktbeschreibung
RIPK1-IN-7 is a highly potent and selective RIPK1 inhibitor with a Kd of 4 nM and an enzymatic IC50 of 11 nM. It demonstrates significant antimetastatic efficacy in vivo, as shown in a B16 melanoma lung metastasis model, making it a valuable tool for researching necroptosis and inflammatory diseases.
Produkteigenschaften
Molekulargewicht:
481.47
Reinheit:
98.18% (May vary between batches)
CAS Nummer:
[2300982-44-7]
Formel:
C25H22F3N5O2
Target-Kategorie:
RIP kinase
Anwendungsbeschreibung
Anwendungsbeschreibung:
Solubility: DMSO:60 mg/mL (124.62 mM),H2O:0.1 mg/mL (0.21 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.15 mM)
