Tat-NR2B9c acetate is a potent, cell-permeable inhibitor of the PSD-95 protein, effectively disrupting its interactions with NMDA receptors (e.g., NR2A/B) and neuronal nitric oxide synthase (nNOS). This neuroprotective peptide is widely used in research models of stroke and neurodegenerative diseases to study excitotoxicity and ischemic damage in both in vitro and in vivo settings.
