Zamicastat, P-gp, P-gp (P-glycoprotein), Pgp, P-glycoprotein, Cluster of differentiation 243, CD243, Breast cancer resistance protein, Dopamine beta-monooxygenase, Dopamine beta-hydroxylase, Dopamine beta-hydroxylase, Dopamine beta-monooxygenase, ABCB1, ABCG2, BIA 5-1058, BCRP, Inhibitor, Multidrug resistance protein 1, inhibit, MDR1
Zamicastat is a dopamine beta-hydroxylase (DBH) inhibitor that also acts as a dual inhibitor of the efflux transporters P-gp and BCRP. This small molecule is used in research to study catecholamine regulation and transporter interactions in both cellular and animal models of cardiovascular and neurological diseases.