Phosphorylation of specific serine or threonine residues is an important post-translational modification for regulating the activity of most proteins. Stimulation of a variety of cell signaling pathways activates the receptor and non-receptor ser/thr kinases that mediate these protein modifications. Antibodies that can detect phosphoserine or phosphothreonine residues are excellent tools for characterizing changes in the post-translational state of a broad range of phosphorylated proteins. Immunoprecipitation of proteins of interest followed by detection of phosphoserine or phosphothreonine using anti-phosphoserine antibody is commonly used to correlate changes in phosphorylation state with alterations in protein activity.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[M380A/M380B]
Isotyp:
IgG1
Puffer:
PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol
Quelle:
PM3801 Phosphoserine/threonine is a mix of two clones: Clone M380A was generated from a phosphothreonine synthetic peptide (coupled to carrier protein)
Target-Kategorie:
Anti-Phosphoserine/threonine
Application Verdünnung:
WB(1:300-5000), IP(1-2ug)
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