Kindlin Polyclonal Antibody, PE Conjugated, Rabbit
Artikelnummer:
BSS-BS-17063R-PE
Hersteller Artikelnummer:
bs-17063R-PE
Alternativnummer:
BSS-BS-17063R-PE-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF
Spezies Reaktivität:
Human, Mouse
Konjugation:
PE
Alternative Synonym:
C20orf42, Chromosome 20 open reading frame 42, DTGCU 2, DTGCU2, FERM1_HUMAN, Fermitin family homolog 1, Fermt1, FLJ20116, FLJ23423, KIND 1, KIND1, Kinderlin, Kindlerin, Kindlin 1, Kindlin syndrome protein, Kindlin-1, Kindlin1, Unc 112 related protein 1, Unc-112-related protein 1, Unc112 related protein, UNC112A, URP 1, URP1.
Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.
