Human CD32 antigen is a glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII0. CD32 mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. It blocks the binding of IgG to Fc gamma RII.
