Recombinant Human Peroxisomal acyl-coenzyme A oxidase 1 protein (113-273AA)
Konjugation:
Unconjugated
Alternative Synonym:
ACOX,acyl-CoA oxidase 1, palmitoyl,acyl-CoA oxidase, straight-chain,acyl-Coenzyme A oxidase 1, palmitoyl,AOX,MITCH,PALMCOX,palmitoyl-CoA oxidase,peroxisomal acyl-coenzyme A oxidase 1,peroxisomal fatty acyl-CoA oxidase,SCOX,straight-chain acyl-CoA oxidase.
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.
