Recombinant Human Diphthine methyltransferase protein (210-325AA)
Konjugation:
Unconjugated
Alternative Synonym:
C9orf112,Diphthamide biosynthesis protein 7,diphthine methyltransferase,RRT2,WD repeat-containing protein 85,WDR85.
Catalyzes the demethylation of diphthine methyl ester to form diphthine, an intermediate diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).
