TSC22D3 Antibody

Artikelnummer: ASB-OACA05934
Artikelname: TSC22D3 Antibody
Artikelnummer: ASB-OACA05934
Hersteller Artikelnummer: OACA05934
Alternativnummer: ASB-OACA05934-100UG,ASB-OACA05934-50UG
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: ELISA, IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant Human TSC22 domain family protein 3 protein (58-134AA)
Konjugation: Unconjugated
Alternative Synonym: delta sleep-inducing peptide immunoreactor,DIP,DSIPI,DSIP-immunoreactive leucine zipper protein,DSIP-immunoreactive peptide,GILZ,glucocorticoid-induced leucine zipper protein,TSC22 domain family protein 3,TSC-22 related protein,TSC-22-like protein,TSC-22R,TSC-22-related protein.
Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity). Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG (By similarity).
Klonalität: Polyclonal
NCBI: 1831
Reinheit: >95%
Formulierung: Liquid
Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue at dilution 1:100
Western blot
All lanes: TSC22D3 antibody at 9ug/ml+ Colo320 whole cell lysate
Seconda