PREX2 Antibody - N-terminal region

Artikelnummer: ASB-ARP71437_P050
Artikelname: PREX2 Antibody - N-terminal region
Artikelnummer: ASB-ARP71437_P050
Hersteller Artikelnummer: ARP71437_P050
Alternativnummer: ASB-ARP71437_P050-25UL,ASB-ARP71437_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PREX2
Alternative Synonym: DEP.2, DEPDC2, P-REX2, PPP1R129
PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. PREX2 mediates the activation of RAC1 in a PI3K-dependent manner. PREX2 may be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 182kDa
NCBI: 80243
UniProt: Q70Z35
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Host: Rabbit
Target Name: PREX2
Sample Type: Hela Whole Cell lysates
Antibody Dilution: 1.0ug/ml
Host: Rabbit
Target Name: PREX2
Sample Tissue: Human Lung Tumor
Antibody Dilution: 1ug/ml
PREX2 Antibody - N-terminal region (ARP71437_P050) in Human Hela using Western Blot