NSMCE4A Antibody - C-terminal region

Artikelnummer: ASB-ARP70964_P050
Artikelname: NSMCE4A Antibody - C-terminal region
Artikelnummer: ASB-ARP70964_P050
Hersteller Artikelnummer: ARP70964_P050
Alternativnummer: ASB-ARP70964_P050-25UL,ASB-ARP70964_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Human
Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NSMCE4A
Alternative Synonym: NS4EA, NSE4A, C10orf86
NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 42kDa
NCBI: 54780
UniProt: Q9NXX6
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-NSMCE4A Antibody
Catalog Number: ARP70964
Formalin Fixed Paraffin Embedded Tissue: Human Adult Small intestine
Observed Staining: Cytoplasm in hepatocytes
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 a€'' 2.0 sec
Host: Rabbit
Target Name: NSMCE4A
Sample Type: HepG2 Whole Cell lysates
Antibody Dilution: 1.0ug/mlNSMCE4A is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells
NSMCE4A Antibody - C-terminal region (ARP70964_P050) in Human HepG2 using Western Blot