TFRC Antibody - N-terminal region
Artikelnummer:
ASB-ARP63719_P050
- Bilder (3)
| Artikelname: | TFRC Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP63719_P050 |
| Hersteller Artikelnummer: | ARP63719_P050 |
| Alternativnummer: | ASB-ARP63719_P050-25UL,ASB-ARP63719_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Human, Rabbit |
| Alternative Synonym: | T9, TR, TFR, p90, CD71, TFR1, TRFR, IMD46 |
| TFRC is a cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
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Rabbit Anti-TFRC Antibody Catalog Number: ARP63719_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Plasma membrane Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-TFRC Antibody Titration: 1.0 ug/ml Positive Control: ACHN Whole Cell |
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TFRC antibody - N-terminal region (ARP63719_P050) in Human ACHN using Western Blot |
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