FCGR3A Antibody - middle region

Artikelnummer: ASB-ARP63559_P050
Artikelname: FCGR3A Antibody - middle region
Artikelnummer: ASB-ARP63559_P050
Hersteller Artikelnummer: ARP63559_P050
Alternativnummer: ASB-ARP63559_P050-25UL,ASB-ARP63559_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Guinea pig, Human, Mouse, Rabbit, Rat
Alternative Synonym: CD16, FCG3, CD16A, FCGR3, IGFR3, IMD20, FCR-10, FCRIII, FCGRIII, FCRIIIA
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 27kDa
NCBI: 2214
UniProt: P08637
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-FCGR3A Antibody
Titration: 1.0 ug/ml
Positive Control: Placenta
Host: Rabbit
Target: FCGR3A
Positive control (+): Mouse Spleen (M-SP)
Negative control (-): Mouse Intestine (M-IN)
Antibody concentration: 1ug/ml
FCGR3A antibody - middle region (ARP63559_P050) in Human Placenta using Western Blot