NRAS Antibody - middle region

Artikelnummer: ASB-ARP63292_P050
Artikelname: NRAS Antibody - middle region
Artikelnummer: ASB-ARP63292_P050
Hersteller Artikelnummer: ARP63292_P050
Alternativnummer: ASB-ARP63292_P050-25UL,ASB-ARP63292_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Alternative Synonym: NS6, CMNS, NCMS, ALPS4, N-ras, NRAS1
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 21kDa
NCBI: 4893
UniProt: P01111
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-NRAS Antibody
Catalog Number: ARP63292_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-NRAS Antibody
Titration: 1.0 ug/ml
Positive Control: Jurkat Whole Cell
NRAS antibody - middle region (ARP63292_P050) in Human Jurkat using Western Blot