Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Alternative Synonym:
BRE, BRCC4, BRCC45
This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.
WB Suggested Anti-BRE Antibody Titration: 1.0 ug/ml Positive Control: A549 Whole CellBRE is strongly supported by BioGPS gene expression data to be expressed in Human A549 cells
BRE antibody - C-terminal region (ARP62254_P050) in Human A549 using Western Blot
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