This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
WB Suggested Anti-AKR1C3 Antibody Titration: 1.0 ug/ml Positive Control: COLO205 Whole CellAKR1C3 is supported by BioGPS gene expression data to be expressed in COLO205
AKR1C3 antibody - N-terminal region (ARP61430_P050) in Human COLO205 using Western Blot
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