VCL Antibody - C-terminal region

Artikelnummer: ASB-ARP61099_P050
Artikelname: VCL Antibody - C-terminal region
Artikelnummer: ASB-ARP61099_P050
Hersteller Artikelnummer: ARP61099_P050
Alternativnummer: ASB-ARP61099_P050-25UL,ASB-ARP61099_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human VCL
Alternative Synonym: MV, MVCL, CMD1W, CMH15, HEL114
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 117kDa
NCBI: 7414
UniProt: P18206
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-VCL Antibody
Catalog Number: ARP61099_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Plasma membrane in intercalated disk
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-VCL Antibody
Titration: 1.0 ug/ml
Positive Control: HepG2 Whole Cell
VCL antibody - C-terminal region (ARP61099_P050) in Human HepG2 using Western Blot