TEF Antibody - N-terminal region

Artikelnummer: ASB-ARP38279_P050
Artikelname: TEF Antibody - N-terminal region
Artikelnummer: ASB-ARP38279_P050
Hersteller Artikelnummer: ARP38279_P050
Alternativnummer: ASB-ARP38279_P050-25UL,ASB-ARP38279_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TEF
TEF (thyrotroph embryonic factor) is a member of the PAR bZip (proline and acidic amino acid-rich basic leucine zipper) transcription factor family. It accumulates with robust circadian rhythms in tissues with high amplitudes of clock gene expression.Thyrotroph embryonic factor (TEF), a transcription factor, is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP), VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 33 kDa
NCBI: 7008
UniProt: Q10587
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunohistochemistry with Skeletal muscle tissue at an antibody concentration of 5ug/ml using anti-TEF antibody (ARP38279_P050)
WB Suggested Anti-TEF Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 0.5 ug/mL of the antibody was used in this experiment. Protein may be phosphorylated.
TEF antibody - N-terminal region (ARP38279_P050) in Human HepG2 using Western Blot