Pias2 Antibody - C-terminal region
Artikelnummer:
ASB-ARP36929_P050
- Bilder (4)
| Artikelname: | Pias2 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP36929_P050 |
| Hersteller Artikelnummer: | ARP36929_P050 |
| Alternativnummer: | ASB-ARP36929_P050-25UL,ASB-ARP36929_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Human, Mouse, Rabbit |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of mouse Pias2 |
| Alternative Synonym: | Di, PI, DIP, Dib, Miz, Miz1, PIAS, SIZ2, ARIP3, PIASxb, AI462206, AU018068, PIASxbeta, PIASxalpha, PIASxalpha6 |
| Pias2 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. It plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It seems to be mostly involved in gene silencing. It binds to sumoylated ELK1 and enhances its transcriptional activity by preventing recruitment of HDAC2 by ELK1, thus reversing SUMO-mediated repression of ELK1 transactivation activity. |
|
|
Mouse Pancreas |
|
|
WB Suggested Anti-Pias2 Antibody Titration: 0.2-1 ug/ml Positive Control: NIH/3T3 cell lysate |
|
|
WB Suggested Anti-Pias2 antibody Titration: 1 ug/mL Sample Type: Human heart |
|
|
Pias2 antibody - C-terminal region (ARP36929_P050) in Mouse NIH-3T3 using Western Blot |
Produktgarantie und fachkundiger Support
