Bovine, Canine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
Immunogen:
The immunogen is a synthetic peptide corresponding to a region of Mouse
Alternative Synonym:
Irf, Irf-1, AU020929
Irf1 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Irf1 acts as a tumor suppressor.