GABRB3 Antibody - middle region
Artikelnummer:
ASB-ARP35339_P050
- Bilder (4)
| Artikelname: | GABRB3 Antibody - middle region |
| Artikelnummer: | ASB-ARP35339_P050 |
| Hersteller Artikelnummer: | ARP35339_P050 |
| Alternativnummer: | ASB-ARP35339_P050-25UL,ASB-ARP35339_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human GABRB3 |
| Alternative Synonym: | ECA5, DEE43, EIEE43 |
| GABRB3 is a member of the ligand-gated ionic channel family. GABRB3 is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism.This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding isoforms with distinct signal peptides have been described. |
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Immunohistochemistry with Lung tissue at an antibody concentration of 5ug/ml using anti-GABRB3 antibody (ARP35339_P050) |
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WB Suggested Anti-GABRB3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Liver |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. In addition to the canonical 54 kDa isoform the peptide is present in a 58 kDa isoform and the protein is glycosylated. |
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Western Blot |
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