P2RX7 Antibody - middle region

Artikelnummer: ASB-ARP35112_P050
Artikelname: P2RX7 Antibody - middle region
Artikelnummer: ASB-ARP35112_P050
Hersteller Artikelnummer: ARP35112_P050
Alternativnummer: ASB-ARP35112_P050-25UL,ASB-ARP35112_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human P2RX7
Alternative Synonym: P2X7
The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 68kDa
NCBI: 5027
UniProt: Q99572
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-P2RX7 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Stomach
WB Suggested Anti-P2RX7 Antibody
Positive Control: Lane 1: 50ug mock transfected HEK-293Lane 2: 50ug hP2X7 transfected HEK-293Lane 3: 50ug mP2X7 transfected HEK-293Lane 4: 50ug rP2X7 transfected HEK-293
Primary Antibody Dilution : 1:625
Secondary Antibody : Anti-rabbit-HRP
Secondry Antibody Dilution : 1:1000
Submitted by: Ronald Sluyter, School of Biological Sciences, University of Wollongong
Host: Rabbit
Target: P2RX7
Positive control (+): Human Placenta (PL)
Negative control (-): 293T (2T)
Antibody concentration: 1ug/ml
P2RX7 antibody - middle region (ARP35112_P050) in Human Stomach using Western Blot