Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human APG4B
Alternative Synonym:
APG4B, AUTL1
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.
WB Suggested Anti-APG4B Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Raji cell lysateATG4B is strongly supported by BioGPS gene expression data to be expressed in Human Raji cells
APG4B antibody - C-terminal region (ARP34434_P050) in Human Raji using Western Blot
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